Debunking the Kava Liver Damage Myth
Myth Tackling the 8 Reported Factors
For years, the idea that kava can cause liver damage has circulated. This myth has caused some to avoid this popular beverage. However, with rigorous scientific evidence, it can be said that kava is safe for consumption.
Below are the 8 commonly cited factors for liver injury related to kava use that warrant nuanced examination based on existing scientific literature:
Misidentification of Cultivar Variation
The claim that different cultivars of the kava plant contain varying levels of toxic constituents has circulated for years. According to the study by Lechtenberg , pipermethystine in concentration levels of 10 mg/kg is not toxic in any animal models. This study scrutinizes the role of pipermethystine in liver toxicity and concludes that it is not a contributing factor.
Use of Inappropriate Plant Parts
Based on the current research, the assertion of “inappropriate plant parts” is debunked. Pipermethystine, the alkaloid found in the upper portion of the plant, was once thought to be toxic, but it has been found non-toxic at levels far exceeding human consumption.
Adulteration and Contamination of Kava Products
Kava products can be inadvertently contaminated by mold hepatotoxins such as aflatoxins. The quantity of fungi present is an important factor in the possible hepatotoxicity of an array of products. However, no new hepatotoxicity-related events have been reported in the past two decades.
Prolonged Treatment Duration
Epidemiological data suggest that kava has been consumed for years without health issues. There is no upper limit of “treatment duration” in which there is a sudden increase in liver-related issues.
Daily Overdose of Kavalactones
Currently, there is no safety guideline at which this is suggested, only efficacy is seen in the reduction of situational stress and anxiety. We technically have no upper dose limit for what is “suggested”.
Co-medication with Other Substances
No research suggests that any drugs consumed could be made further toxic with the inclusion of kavalactones at human concentrations. Furthermore, there is no evidence indicating that kavalactones interact with the pharmacokinetics of drugs.
Alcohol Use
Alcohol is a known liver toxin, and the combination of long-term consumption of alcohol and kava would cause no more liver issues than alcohol consumed alone. It should be understood that although we do not have convincing evidence that kava and alcohol are toxic to the liver, we do not have subsequent research regarding other organs that may be affected.
Preexisting Liver Disease
No research has suggested preexisting liver disease as a comorbidity in kava consumption. If liver disease exists, it is a preexisting condition.
In summary, while caution is advisable, many of the traditionally cited factors for liver injury related to kava use are not supported by rigorous scientific evidence.
Now you can enjoy your noble kava without fear of liver injury and misinformation.